Nasal Polyposis Causes And Treatment

In nasal polyps patients, the role that nasal nitric oxide (nNO) plays in sinonasal diseases is increasingly appreciated. To test the diagnostic value of measuring nNO levels in a symptomatic population undergoing evaluation for potential chronic rhinosinusitis with nasal polyps.

Of the patients referred to an outpatient allergy clinic for persistent nasal symptoms, those reporting nasal blockage plus 1 or more additional symptoms (discolored discharge, anterior or postnasal drip, facial pain or pressure, and reduction or loss of smell) were categorized as having CRS according to sinus computed tomography scores, with nasal polyps on the basis of endoscopic signs. All the included patients underwent nNO measurement and skin prick tests for common inhalant allergens. Healthy individuals served as controls for nNO measurement.

Results :Levels of nNO were significantly lower in patients with nasal polyps (median, 340 ppb; 25th-75th percentile, 145–390 ppb) . Low values of nNO separated very well patients with nasal polyps, and the nNO cutoff value of less than 442 ppb was associated with the best combination of specificity (91%) and sensitivity (87%), resulting in a negative predictive value of 91% and a positive predictive value of 87%. A significant inverse relationship was observed between nNO level and sinus computed tomography score (r2 = −0.39, P < .001).

Testing for nNO is highly predictive of nasal polyps in a selected population of patients with symptoms suggestive of CRS.View on the problem of nasal polyps and their treatment in historical perspective are presented with full particulars. Pathophysiology of nasal polyposis historically is mentioned. Destruction of nasal polyps by chemical compounds were recommended before the surgical treatment. But natural treatment will the next step for us to get rid of nasal polyps

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